RefleXion takes the best positron emission tomography (PET) imaging offers and combines it with stereotactic radiotherapy for a significant advancement in radiotherapy delivery.

Biology-guided Radiotherapy

RefleXion’s biology-guided radiotherapy (BgRT) is the first to utilize both anatomic (computed tomography) and functional (positron emission tomography) imaging data to guide personalized radiotherapy.

Potential of PET Tracers

PET tracers can identify the metabolic activity and other distinct biological characteristics of tumors such as specific biomarker antigens (e.g., PSMA) or even probe the immune system itself (e.g., PDL1 expression or activated T-cells).

Significant Advancement

RefleXion’s approach represents a significant advance for patients and uniquely leverages a proven modality for visualizing cancer with one of the most effective ways to treat cancer.

Why is biology-guided radiotherapy important?

The combination of PET and radiotherapy at the time of treatment has the potential to positively impact the lives of millions of patients around the world.

Scientific Meeting Abstracts

PSMA-directed biologically-guided radiation therapy of castration-sensitive oligometastatic prostate cancer patients

R. Phillips, A. Da Silva, N. Radwan, M. Gorin, S. Rowe, K. Pienta, M. Pomper, J. Wong, P. T. Tran, K. Wang; Johns Hopkins Medicine, Baltimore, MD, RefleXion Medical, Inc., Hayward, CA, Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD

Dosimetric evaluation of treatment plans for a biology-guided radiotherapy system in treatment of nasopharyngeal cancer

C. Han, A. Liu, J. Liang, A. Da Silva, S. Zhang, and J.Y.C. Wong; City of Hope National Medical Center, Duarte, CA, RefleXion Medical, Inc., Hayward, CA

Evaluation of a prototype treatment planning system (TPS) for biology-guided radiotherapy (BgRT) in the context of stereotactic body radiation therapy (SBRT) for oligo-metastases

J. Partouche, S.J. Chmura, J.J. Luke, A. Da Silva, and B. Aydogan; University of Chicago, Chicago, IL, RefleXion Medical, Inc., Hayward, CA

Use of Emission Guided Radiation Therapy Can Better Spare Critical Structures Compared With Intensity Modulated Radiation Therapy, Volumetric Modulated Arc Therapy, or Proton Therapy

S.N. Seyedin, O.R. Mawlawi, L.M. Turner, S. Mazin, Y. Voronenko, P.D. Olcott, C.A. Wages, P. Balter, J.Y. Chang, D.R. Gomez, R.U. Komaki, J.W. Welsh

A Dosimetric Study to Assess the Feasibility of Prototype Treatment Planning Software for a New Biology-guided Radiotherapy System

J. Liang, A. Liu, C. Han, A. Da Silva, S. Zhang, and J.Y.C. Wong; City of Hope National Medical Center, Duarte, CA, RefleXion Medical, Inc.